Application of real-time PCR-based multicolor melting curve with automatic analysis system in pregestational and prenatal thalassemia diagnoses.

Xue-Wei TangFan JiangJian LiXiao-Mei LinJian-Ying ZhouJun-Hui WanLian-Dong ZuoYan-Xia QuFa-Tao LiGui-Lan ChenDong-Zhi Li

Published in: Annals of human genetics (2023)

MMCA can be an alternative approach used in routine thalassemia carrier screening and prenatal diagnosis for its high throughput, sufficient stability, low cost, and easy operation.

Keyphrases

low cost
real time pcr
high throughput
sickle cell disease
high resolution
pregnant women
deep learning
clinical practice
mass spectrometry
neural network