Analysis of degradation products of nerve agents in biological fluids by ion chromatography-tandem mass spectrometry.
Mai OtsukaHajime MiyaguchiPublished in: Forensic toxicology (2022)
RMPAs could be sufficiently analyzed by IC-MS/MS. In addition, the limits of detection were superior to those obtained in our previous study involving LC-MS/MS or derivatization-LC-MS/MS method. For analysis of biological samples, an appropriate pretreatment method can be chosen according to the amount of sample available for analysis and expected RMPA concentrations.
Keyphrases
- tandem mass spectrometry
- ultra high performance liquid chromatography
- high performance liquid chromatography
- liquid chromatography
- simultaneous determination
- gas chromatography
- solid phase extraction
- ms ms
- liquid chromatography tandem mass spectrometry
- mass spectrometry
- high resolution mass spectrometry
- high resolution
- gas chromatography mass spectrometry
- high speed
- label free
- loop mediated isothermal amplification
- quantum dots