Special Issue: "Functionalized Nanomaterials and Structures for Biomedical Applications".
Paul Cătălin BalaurePublished in: Materials (Basel, Switzerland) (2023)
Nanoscale drug formulations are under wider and wider investigation due to their multiple unique advantages, such as stealth properties which avoid opsonization in the blood stream; specific ligand guided drug delivery to injured cells and tissues; on-demand release in sharp response to a series of endogenous and exogenous stimuli, allowing for predetermined programmed delivery to specific loci in the body and possible timing with circadian rhythms; increased cellular uptake due to their small dimensions and the possibility of intracellular delivery of the therapeutic cargo, especially when functionalized with cell penetrating agents; increased stability in biological fluids; augmented bioavailability; and tailored pharmacokinetics and pharmacodynamics [...].
Keyphrases
- drug delivery
- induced apoptosis
- quantum dots
- cell cycle arrest
- single cell
- genome wide
- cell therapy
- molecularly imprinted
- emergency department
- cancer therapy
- endoplasmic reticulum stress
- high resolution
- stem cells
- cell death
- mass spectrometry
- signaling pathway
- oxidative stress
- drug induced
- mesenchymal stem cells
- genome wide association study