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A novel pathogenic variation of DOCK6 gene: the genotype-phenotype correlation in Adams-Oliver syndrome.

Lula María Nieto-BenitoRicardo Suárez-FernándezMinia Campos-Domínguez
Published in: Molecular biology reports (2023)
In AOS, genotype-phenotype correlations have been described. DOCK6 mutations appear to be related with congenital cardiac and central nervous system malformations associated with intellectual disability, as illustrated in the present case.
Keyphrases
  • intellectual disability
  • autism spectrum disorder
  • left ventricular
  • copy number
  • cerebrospinal fluid
  • case report
  • heart failure
  • dna methylation
  • atrial fibrillation
  • transcription factor
  • genome wide analysis