Altered Serotonin 1B Receptor Binding After Escitalopram for Depression Is Correlated With Treatment Effect.
M GärdeG J MathesonK VarnäsP SvenningssonE Hedman-LagerlöfJ LundbergL FardeM TigerPublished in: The international journal of neuropsychopharmacology (2024)
Our findings align with the previously reported reduction of 5-HT1B receptor binding in the raphe nuclei after SSRI administration and support future studies testing change in DBS 5-HT1B receptor binding as an SSRI treatment response marker.