Combined SEPT9 and BMP3 methylation in plasma for colorectal cancer early detection and screening in a Brazilian population.

Adhara Brandão LimaMariana Bisarro Dos ReisMarcus MatsushitaMonise Tadin Dos ReisMarco Antônio de OliveiraRui Manuel Vieira Reis Denise Peixoto Guimarães

Published in: Cancer medicine (2023)

The present study suggests that a combination of SEPT9 and BMP3 plasma methylation, along with age over 60 years, showed the highest performance in detecting CRC in a Brazilian population. These noninvasive biomarkers can potentially serve as useful tools for CRC screening programs.

Keyphrases

mesenchymal stem cells
dna methylation
genome wide
public health
bone regeneration
gene expression