Login / Signup

Gold Ion Beam Milled Gold Zero-Mode Waveguides.

Troy C MessinaBernadeta R SrijantoCharles Patrick CollierIvan I KravchenkoChristopher I Richards
Published in: Nanomaterials (Basel, Switzerland) (2022)
Zero-mode waveguides (ZMWs) are widely used in single molecule fluorescence microscopy for their enhancement of emitted light and the ability to study samples at physiological concentrations. ZMWs are typically produced using photo or electron beam lithography. We report a new method of ZMW production using focused ion beam (FIB) milling with gold ions. We demonstrate that ion-milled gold ZMWs with 200 nm apertures exhibit similar plasmon-enhanced fluorescence seen with ZMWs fabricated with traditional techniques such as electron beam lithography.
Keyphrases
  • single molecule
  • electron microscopy
  • atomic force microscopy
  • living cells
  • monte carlo
  • energy transfer
  • high resolution
  • photodynamic therapy
  • liver fibrosis