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Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of Exacerbations.

Martina SundqvistKristina AndelidAnn Ekberg-JanssonJohan BylundAnna Karlsson-BengtssonAnders Lindén
Published in: International journal of chronic obstructive pulmonary disease (2021)
Systemic Galectin-3 is increased in a reproducible but modest manner during exacerbations in smokers with COPD-CB. During stable clinical conditions, the level of systemic Galectin-3 does not distinguish patients that remain clinically stable from those that develop exacerbations. This makes it less likely that systemic Galectin-3 may become a clinically useful biomarker in the current setting.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • cystic fibrosis
  • end stage renal disease
  • smoking cessation
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • prognostic factors