Targeting the KRAS, p38α, and NF-κB in lung adenocarcinoma cancer cells: The effect of combining RNA interferences with a chemical inhibitor.

Habib ZarredarShadi PashapourSafar FarajniyaKhalil AnsarinBehzad BaradaranVahideh AhmadzadehFatemeh Safari

Published in: Journal of cellular biochemistry (2019)

The results of this study indicated that p38α, KRAS, and NF-κB signaling pathways might play an important role in the development and growth of lung cancer and might be a potential therapeutic target for treatment of lung cancer.

Keyphrases

signaling pathway
pi k akt
lps induced
oxidative stress
wild type
nuclear factor
induced apoptosis
inflammatory response
immune response