Universal genotyping reveals province-level differences in the molecular epidemiology of tuberculosis.

Jennifer L GuthrieAlex Marchand-AustinKirby CroninKaren LamDaria PyskirClare KongDanielle JorgensenMabel RodriguesDavid RothPatrick TangVictoria J CookJames JohnstonFrances B JamiesonJennifer L Gardy

Published in: PloS one (2019)

We recommend expanding analysis of shared genotypes to include neighbouring jurisdictions, and implementing whole genome sequencing to improve identification of TB transmission, recognize outbreaks, and monitor changing trends in TB epidemiology.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
south africa
genome wide
high throughput
risk factors
quality improvement
hiv aids
infectious diseases
emergency department
gene expression
human immunodeficiency virus