Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in Gothenburg.
Anna DittrichNicholas James AshtonHenrik ZetterbergKaj BlennowAnna ZettergrenJoel SimrénTobias SkillbäckSara ShamsAlejandra MachadoErik WestmanMichael SchöllIngmar SkoogSilke KernPublished in: Neurology (2023)
In a community-based cohort of 70-year olds, P-NfL was associated with both prevalent and incident CKD, while CSF and/or imaging measures did not differ by CKD status. Participants with CKD and dementia presented similar levels of P-NfL.