Changes in body weight, adherence, and appetite during 2 years of calorie restriction: the CALERIE 2 randomized clinical trial.

James L DorlingSai Krupa DasSusan B RacetteJohn W ApolzanDachuan ZhangCarl F PieperCorby K Martinnull null

Published in: European journal of clinical nutrition (2020)

In individuals who are nonobese, adherence to 25% CR declines after 20 weeks, but 2 years of CR that stimulates a meaningful reduction in weight, promotes aging-related benefits and negligibly affects appetite is viable.

Keyphrases

body weight
weight loss
glycemic control
type diabetes
physical activity
clinical trial
body mass index
metabolic syndrome
adipose tissue
double blind
insulin resistance