Identification of sesquiterpene synthases from the Basidiomycota Coniophora puteana for the efficient and highly selective β-copaene and cubebol production in E. coli.

Wolfgang Mischko Max Hirte Monika Fuchs Norbert Mehlmer Thomas Bartholomäus Brück

Published in: Microbial cell factories (2018)

The reported product selectivity and our generated terpene titers exceed all published biotechnological data regarding the production of β-copaene and cubebol. This represents a promising and economic alternative to extraction from natural plant sources and the associated complex product purification.

Keyphrases

escherichia coli
electronic health record
big data
machine learning
bioinformatics analysis
structural basis