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Sex-specific differences in left ventricular mass and myocardial energetic efficiency in non-diabetic, pre-diabetic and newly diagnosed type 2 diabetic subjects.

Elena SuccurroSofia MiceliTeresa Vanessa FiorentinoAngela SciacquaMaria PerticoneFrancesco AndreozziGiorgio Sesti
Published in: Cardiovascular diabetology (2021)
Left ventricle is subject to maladaptive changes with worsening of glucose tolerance, especially in women with newly diagnosed T2DM. The sex-specific increase in LVM and decrease in MEEi, both being predictors of CVD, may have a role in explaining the stronger impact of T2DM on the excess risk of CVD in women than in men.
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