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Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons.

Nathalie StakenborgEvelien LabeeuwPedro J Gomez-PinillaSebastiaan De SchepperRaymond AertsGera GoverseGiovanna FarroIris AppeltansElisa MeroniMichelle StakenborgMaria Francesca ViolaErika Gonzalez-DominguezGoele BosmansYeranddy A AlpizarAlbert WolthuisAndre D'HooreKim Van BeekSimon VerheijdenMarleen VerhaegenRita DeruaEtienne WaelkensMilena MorettiCecilia GottiPatrick AugustijnsKarel TalaveraPieter Vanden BergheGianluca MatteoliGuy E Boeckxstaens
Published in: Gut (2018)
NCT02425774.
Keyphrases
  • patients undergoing
  • oxidative stress
  • spinal cord
  • spinal cord injury