IgG4-positive plasma cells are more often detected in chronic periapical lesions arising from permanent rather than primary teeth.
Xiomara Beatriz Jimenez PolancoA S BertassoHeitor Albergoni SilveiraLuciana Yamamoto de AlmeidaLana Kei Yamamoto de AlmeidaRaquel Assed Bezerra da Silva SegatoLéa Assed Bezerra da SilvaAndiara De RossiPaulo Nelson FilhoJorge Esquiche LeónPublished in: International endodontic journal (2021)
There were slight variations in the Ig light and heavy chain profiles in chronic periapical lesions when comparing the permanent and primary dentitions. The ability of IgG4+ plasma cell infiltration to modulate inflammatory responses in chronic periapical lesions arising from permanent as opposed to primary teeth should be considered in future studies.