Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating Allergic Rhinitis Mouse Model based on Network Pharmacology and Molecular Docking.

Sihong HuangYue Huang

Published in: Current computer-aided drug design (2024)

The YJT formula has therapeutic effects in an allergic rhinitis mouse model, with the main active components being quercetin, aloe-emodin, and denudanolide b, and the key targets being IL6, AKT1, IL1B, VEGFA, and PTGS2, involving multiple signaling pathways.

Keyphrases

allergic rhinitis
mouse model
molecular docking
signaling pathway
molecular dynamics simulations
human milk
cell proliferation
pi k akt
low birth weight
induced apoptosis
risk assessment
oxidative stress
preterm infants