Opportunities and challenging issues of nanomaterials in otological fields: an occupational health perspective.
Veruscka LesoLuca FontanaMaria Luigia ErcolanoRosaria RomanoIvo IavicoliPublished in: Nanomedicine (London, England) (2019)
Nanotechnology may offer innovative solutions to overcome the physiological and anatomical barriers that make the diagnosis and treatment of ear diseases an extremely challenging issue. However, despite the solutions provided by nano-applications, the still little-known toxicological behavior of nanomaterials raised scientific concerns regarding their biosafety for treated patients and exposed workers. Therefore, this review provides an overview on recent developments and upcoming opportunities in nanoscale otological applications, and critically assesses possible adverse effects of nanosized compounds on ear structures and hearing functionality. Although such preliminary data do not allow to draw definite strategies for the evaluation of nanomaterial ototoxicity, they can still be useful to improve scientific community and workforce awareness regarding possible nanomaterial adverse effects on ear.
Keyphrases
- public health
- healthcare
- end stage renal disease
- newly diagnosed
- mental health
- ejection fraction
- chronic kidney disease
- prognostic factors
- high resolution
- big data
- health information
- patient reported outcomes
- deep learning
- risk assessment
- artificial intelligence
- mass spectrometry
- single molecule
- social media
- health promotion