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Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse.

Mengyao YuSergiy KyryachenkoStephanie DebettePhillippe AmouyelJean-Jacques SchottThierry Le TourneauChristian DinaRussell A NorrisAlbert A HagègeXavier JeunemaitreNabila Bouatia-Naji
Published in: Circulation. Genomic and precision medicine (2021)
We report an updated meta-analysis genome-wide association study for MVP using dense imputation coverage and an improved case-control sample. We describe several loci and genes with MVP spanning biological mechanisms highly relevant to MVP, especially during valve and heart development.
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