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1 H, 13 C and 15 N resonance assignments of stress granule key component G3BP1 RRM domain.

Hanyu ZhangXiaoming TuJiahai Zhang
Published in: Biomolecular NMR assignments (2022)
G3BP1 exists as a helicase and one of the core components in stress granules, which are associated with a variety of neurodegenerative diseases. Its RNA recognition motif (RRM) domain performs the paramount function of binding mRNA. Here we report the resonance assignment of human G3BP1 RRM domain to understand its structure-function relationship.
Keyphrases
  • energy transfer
  • endothelial cells
  • stress induced
  • binding protein
  • induced pluripotent stem cells
  • transcription factor
  • dna binding