Renal Ischemia/Reperfusion Mitigation via Geraniol: The Role of Nrf-2/HO-1/NQO-1 and TLR2,4/MYD88/NFκB Pathway.

Maged Elsayed Mohamed Mohammed A Elmorsy Nancy S Younis

Published in: Antioxidants (Basel, Switzerland) (2022)

Geraniol might protect against renal I/R via the inhibition of the TLR2,4/MYD88/NFκB pathway, mediating anti-inflammation and activation of the Nrf2 pathway, intervening in antioxidative activities.

Keyphrases

oxidative stress
toll like receptor
nuclear factor
inflammatory response
signaling pathway
lps induced
pi k akt
immune response
climate change