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High prevalence of de novo metabolic dysfunction-associated fatty liver disease after liver transplantation and the role of controlled attenuation parameter.

Lung-Yi MakAlbert Cy ChanTiffany Cho-Lam WongWing-Chiu DaiWong-Hoi SheKa-Wing MaSui-Ling SinKa-Wan ChuWai Kay SetoMan Fung YuenChung Mau LoJames Yan-Yue Fung
Published in: BMC gastroenterology (2023)
Although NAFLD remains an uncommon primary liver disease indication for LT in Chinese patients, post-transplant de novo graft steatosis is common and the majority is classified as MAFLD. Development of graft steatosis is not associated with an increase in graft fibrosis but was associated with worse metabolic control and graft dysfunction. Routine CAP measurement to detect de novo graft steatosis should be considered after LT regardless of the primary indication of LT.
Keyphrases
  • insulin resistance
  • high fat diet
  • oxidative stress