Multimodal epigenetic sequencing analysis (MESA) of cell-free DNA for non-invasive colorectal cancer detection.
Yumei LiJianfeng XuChaorong ChenZhenhai LuDesen WanDiange LiJason S LiAllison J SorgCurt C RobertsShivani MahajanMaxime A GallantItai PinkoviezkyYa CuiDavid J TaggartWeibo XiePublished in: Genome medicine (2024)
Together, MESA stands as a major advancement in the field by utilizing comprehensive and complementary epigenetic profiles of cfDNA for effective non-invasive cancer detection.