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Effects of the dutasteride and sildenafil association in the penis of a benign prostatic hyperplasia animal model.

Marcello Henrique Araújo da SilvaJorge L MedeirosWaldemar S CostaFrancisco J B SampaioDiogo Benchimol de Souza
Published in: The aging male : the official journal of the International Society for the Study of the Aging Male (2019)
Treatment with dutasteride promoted morphological changes in the corpus cavernous of this BPH model. Concomitant treatment with sildenafil did not prevent the morphological changes caused by dutasteride; on the contrary, it also promoted a further increase in elastic fibers.
Keyphrases
  • benign prostatic hyperplasia
  • lower urinary tract symptoms
  • pulmonary hypertension
  • pulmonary arterial hypertension
  • combination therapy