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Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2-related factor 2 signalling in ischaemic stroke.

Chuanhong WuJianxin ChenRuocong YangFeipeng DuanShaojing LiXiuping Chen
Published in: British journal of pharmacology (2018)
Our results demonstrated that Nef might have therapeutic potential for ischaemic stroke and may exert its protective role through mitochondrial protection. This protection might be attributed to the modulation of Nrf2 signalling.
Keyphrases
  • nuclear factor
  • oxidative stress
  • toll like receptor
  • immune response
  • inflammatory response