Childhood trauma moderates schizotypy-related brain morphology: analyses of 1182 healthy individuals from the ENIGMA schizotypy working group.

Yann Quidé Oliver J Watkeys Emiliana Tonini Dominik Grotegerd Udo Dannlowski Igor Nenadić Tilo T J Kircher Axel Krug Tim Hahn Susanne Meinert Janik Goltermann Marius Gruber Frederike Stein Katharina Brosch Adrian Wroblewski Florian Thomas-OdenthalPaula UsemannBenjamin Straube Nina Alexander Elisabeth Johanna Leehr Jochen Bauer Nils Ralf Winter Lukas Fisch Katharina Dohm Wulf Rössler Lukasz Smigielski Pamela DeRosseAshley MoyettJosselin Houenou Marion Leboyer James Gilleen Sophia I Thomopoulos Paul M Thompson Andre Aleman Gemma Modinos Melissa Jane Green

Published in: Psychological medicine (2023)

These results suggest that alterations in brain regions critical for higher cognitive and integrative processes that are associated with schizotypy may be enhanced in individuals exposed to high levels of trauma.

Keyphrases

resting state
white matter
functional connectivity
trauma patients
cerebral ischemia
multiple sclerosis
network analysis
drug induced