A month in the country: The sesquicentenary of David Ferrier's classical cerebral localisation researches of 1873.

The experimental studies of David Ferrier (1843-1928), establishing many of the principles of cerebral localisation which still underpin neurological reasoning in clinical practice, were first reported 150 years ago. This paper briefly reviews Ferrier's experimental work, first undertaken in the laboratory at the West Riding Lunatic Asylum in Wakefield, West Yorkshire and his resulting publications of 1873, as well as some contemporaneous responses to his findings. These not only established 'motor centres' pertinent to physiology and the signs of cerebral disease but also, from the outset, had ramifications for Ferrier's understanding of higher mental functions. That linguistic, mnemonic and perceptual cognitive functions might be related to localised areas within the brain received its most emphatic initial impetus from Ferrier's work.