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Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondria transfer.

Trenton LippertCesario Venturina Borlongan
Published in: CNS neuroscience & therapeutics (2019)
This study shows that HBOT preconditioning stands as a robust prophylactic treatment for sequestration of inflammation inherent in stroke and TBI, possibly facilitating the transfer of resilient mitochondria from astrocytes to inflammation-susceptible neuronal cells in mitigating cell death.
Keyphrases
  • cell death
  • inflammatory response
  • traumatic brain injury
  • cell cycle arrest
  • cell proliferation
  • induced apoptosis
  • radiation therapy
  • cerebral ischemia
  • reactive oxygen species