Prognostic impact of pretreatment cytogenetics in adult Philadelphia chromosome-negative acute lymphoblastic leukemia in the era of minimal residual disease.

Ghayas C IssaHagop M KantarjianC Cameron YinWei QiaoFarhad RavandiDeborah ThomasNicholas J ShortKoji SasakiGuillermo Garcia-ManeroTapan M KadiaJorge E CortesNaval DaverGautam BorthakurNitin JainMarina KonoplevaIssa KhouriPartow KebriaeiRichard E ChamplinSherry PierceSusan M O'BrienElias Jabbour

Published in: Cancer (2016)

A complex karyotype and Ho-Tr are adverse prognostic factors for adults with ALL independently of the MRD status. These findings suggest that pretreatment cytogenetics remain a valuable prognostic tool in this population. Cancer 2017;123:459-467. © 2016 American Cancer Society.

Keyphrases

acute lymphoblastic leukemia
prognostic factors
papillary thyroid
squamous cell
childhood cancer
squamous cell carcinoma
emergency department
gene expression
signaling pathway
genome wide
acute myeloid leukemia
drug induced