CADASIL: Migraine, Encephalopathy, Stroke and Their Inter-Relationships.
Rhea Yan Ying TanHugh Stephen MarkusPublished in: PloS one (2016)
Migraine with aura is a prominent feature of CADASIL. Treatment responses are similar to those seen in the general migraine population and no complications were observed with triptans. Migraine with aura was associated with increased risk of encephalopathy suggesting they may share pathophysiological mechanisms. There was no increased stroke risk associated with migraine, but risk appeared to be reduced although this finding needs confirming.