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Emergence of bedaquiline-resistance in a high-burden country of tuberculosis.

Elena ChesovDumitru ChesovFlorian P MaurerSönke AndresChristian UtpatelIvan BarilarAna DonicaMaja ReimannStefan NiemannChristoph LangeValeriu CruduJan HeyckendorfMatthias Merker
Published in: The European respiratory journal (2021)
MDR-TB treatments based on bedaquiline require a functional background regimen to achieve high cure rates and to prevent the evolution of bedaquiline resistance. Novel MDR-TB therapies with bedaquiline require timely and comprehensive drug resistance monitoring.
Keyphrases
  • multidrug resistant
  • drug resistant
  • mycobacterium tuberculosis
  • pulmonary tuberculosis
  • risk factors
  • hiv aids
  • human immunodeficiency virus
  • antiretroviral therapy