Progressive grey matter alterations in bipolar disorder across the life span - a systematic review.
Katharina FörsterRosa Hannele HorstmannUdo DannlowskiJosselin HouenouPhilipp KanskePublished in: Bipolar disorders (2023)
The evidence collected suggests that the progression of BD impairs paediatric brain development and accelerates structural brain decline across the lifespan. Age-specific changes in amygdala volume in paediatric BD suggests that reduced amygdala volume is a correlate of early onset BD. Clarifying the role of BD in brain-development across the life span promises a deeper understanding of the progression of BD patients through different developmental episodes.
Keyphrases
- resting state
- early onset
- functional connectivity
- white matter
- bipolar disorder
- end stage renal disease
- intensive care unit
- multiple sclerosis
- late onset
- emergency department
- chronic kidney disease
- newly diagnosed
- ejection fraction
- major depressive disorder
- peritoneal dialysis
- prefrontal cortex
- stress induced
- patient reported outcomes
- temporal lobe epilepsy
- blood brain barrier
- subarachnoid hemorrhage