SHED-exos promote saliva secretion by suppressing p-ERK1/2-mediated apoptosis in glandular cells.

Wei-Xia ChuChong DingZhi-Hao DuPan WeiYi-Xiang WangXue-Jun GeGuang-Yan Yu

Published in: Oral diseases (2023)

SHED-exos suppress epithelial cell death, which is responsible for promoting salivary secretion. SHED-exos inhibited inflammation-triggered epithelial cell apoptosis by suppressing p-ERK1/2 activation, which is involved in these effects.

Keyphrases

cell cycle arrest
pi k akt
cell death
signaling pathway
cell proliferation
induced apoptosis
oxidative stress