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Chelator impact: investigating the pharmacokinetic behavior of copper-64 labeled PD-L1 radioligands.

Fabian KrutzekCornelius K DonatSven Stadlbauer
Published in: EJNMMI radiopharmacy and chemistry (2024)
Cu]Cu-14 exhibited favorable renal clearance; however, the limited uptake in tumors suggests the need for structural modifications to the binding motif for future PD-L1 radiotracers.
Keyphrases
  • aqueous solution
  • metal organic framework
  • current status
  • pet imaging
  • binding protein