Histopathological evaluation of minor salivary gland papillary-cystic tumours: focus on genetic alterations in sialadenoma papilliferum and intraductal papillary mucinous neoplasm.

Masato NakaguroMakoto UranoIkuko OgawaHideaki HiraiYoshinari YamamotoHiroshi YamaguchiMaki TanigawaJun MatsubayashiHiroshi HiranoJunji ShibaharaYuichiro TadaToyonori TsuzukiYasuo OkadaYuichiro SatoKenichiro IkedaAoi SukedaYumi HondaYoshiki MikamiToshitaka Nagao

Published in: Histopathology (2019)

The appropriate interpretation of histological findings and specific genetic alterations (e.g. BRAF V600E and AKT1 E17K in SP and IPMN) would be useful for the correct diagnosis of minor salivary gland papillary-cystic tumours.

Keyphrases

clear cell
low grade
genome wide
copy number
signaling pathway
cell proliferation
dna methylation
gene expression