IL-17 Mildly Rescued the Impaired Proliferation of Alveolar Epithelial Cells Induced by LCN2 Overexpression.

Tingting Lv Ziliang HouKaiyuan YangJinxiang Wang

Published in: Canadian respiratory journal (2024)

The results revealed the reversed effect of IL-17 on the impaired proliferative capacity of the alveolar epithelium induced by LCN2 overexpression. The target alveolar epithelial cells regulated by this process were AT2 cells, providing new clues for alveolar epithelium repair after injury and the treatment of lung injury diseases.

Keyphrases

cell proliferation
induced apoptosis
transcription factor
cell cycle arrest
oxidative stress
combination therapy
replacement therapy