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TRAV26-2 T CELL RECEPTOR EXPRESSION IS ASSOCIATED WITH MUCOSAL LYMPHOCYTE RESPONSE TO WHEAT PROTEINS IN FUNCTIONAL DYSPEPSIA PATIENTS.

Grace L BurnsMichael PotterAndrea MatheJessica BruceKyra MinahanJessica L BarnesJennifer PryorCheenie NievaSimonne SherwinAnnalisa CuskellyThomas FairlieRaquel CameronSteven BollipoMudar Zand IraniRobert FosterLay T GanAyesha ShahNatasha KoloskiPaul S FosterJay C HorvatMarjorie M WalkerNick PowellMartin VeyseyKerith DuncansonGerald HoltmannNicholas J TalleySimon Keely
Published in: Clinical and translational gastroenterology (2023)
Our findings suggest that gliadin exposure provokes a duodenal effector Th2-like response in FD patients, supporting the notion that food antigens drive responses in some patients. Further, these findings suggest that altered lymphocyte responses to wheat proteins play a role in FD pathogenesis.
Keyphrases
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • chronic kidney disease
  • peritoneal dialysis
  • prognostic factors
  • patient reported outcomes
  • dendritic cells
  • climate change