Anti-Neutrophil Extracellular Trap Antibodies and Impaired Neutrophil Extracellular Trap Degradation in Antiphospholipid Syndrome.
Yu ZuoSrilakshmi YalavarthiKelsey GockmanJacqueline A MadisonJohann E GudjonssonJ Michelle KahlenbergW Joseph McCunePaula L BockenstedtEdward M BehrensChristian LoodPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Our data indicate high levels of anti-NET antibodies in patients with primary APS, which may impair NET clearance and activate the complement cascade. These findings may ultimately enable more effective risk stratification.