Inhibitory anti ADAMTS13 antibodies with a new rapid fully automated CLiA assay.

Barbara MontaruliChiara NovelliLaura SolfiettiAlessandra ValpredaMario BazzanIvo Luigi Andrea BeverinaBruno BrandoDario RoccatelloDomenico Cosseddu

Published in: International journal of laboratory hematology (2020)

CliA and ELISA Bethesda assays showed very good agreement with samples run at the same time using ELISA ADAMTS13-autoantibody assay. Albeit more expensive, the CliA Bethesda assay identified inhibitory anti-ADAMTS13 within almost the same TAT as ELISA, but with better automation and limited operator involvement.

Keyphrases

high throughput
fine needle aspiration
monoclonal antibody
single cell
deep learning
ultrasound guided
quantum dots