The presence of T2DM does not increase the risk of CRC or IBD. Moreover, T2DM might reduce risk of IBD, including UC. Conversely, the occurrence of CRC or IBD does not influence the risk of T2DM. The association between T2DM and IBD/UC may be related to the changes in multiple metabolic pathways and CTLA-4-mediated immune response.
Keyphrases
- glycemic control
- ulcerative colitis
- immune response
- bioinformatics analysis
- risk assessment
- genome wide
- cardiovascular disease
- metabolic syndrome
- adipose tissue
- dendritic cells
- inflammatory response
- toll like receptor
- human immunodeficiency virus
- cardiovascular risk factors
- men who have sex with men
- hepatitis c virus