Association between single nucleotide polymorphism SLCO1B1 gene and simvastatin pleiotropic effects measured through flow-mediated dilation endothelial function parameters.

null AndriantoMia PuspitasariMeity ArdianaIvana Purnama DewiKhubay Alvia ShonafiLouisa Fadjri Kusuma WardhaniRicardo Adrian Nugraha

Published in: Therapeutic advances in cardiovascular disease (2022)

There was no association between FMD and the SNP c.521T>C (TC genotype). The duration of simvastatin medication and systolic blood pressure were both associated to FMD.

Keyphrases

blood pressure
genome wide
hypertensive patients
heart failure
heart rate
left ventricular
healthcare
copy number
dna methylation
gene expression
adverse drug
type diabetes
high density
blood glucose
adipose tissue
insulin resistance
electronic health record
drug induced