3' untranslated region of Ckip-1 inhibits cardiac hypertrophy independently of its cognate protein.

Yinlong ZhaoShukuan LingJianwei LiGuohui ZhongRuikai DuYouyou LiYanqing WangCaizhi LiuXiaoyan JinWei LiuTong LiuYuheng LiDingsheng ZhaoWeijia SunZizhong LiuZifan LiuJunjie PanXinxin YuanXingcheng GaoWenjuan XingYan-Zhong ChangYingxian Li

Published in: European heart journal (2021)

These findings disclose that Ckip-1 3' UTR inhibits cardiac hypertrophy independently of its cognate protein. Ckip-1 3' UTR is an effective RNA-based therapy tool for treating cardiac hypertrophy and heart failure.

Keyphrases

heart failure
heat shock
protein protein
binding protein
small molecule
nucleic acid