High-flow nasal oxygen in resource-constrained, non-intensive, high-care wards for COVID-19 acute hypoxaemic respiratory failure: Comparing outcomes of the first v. third waves at a tertiary centre in South Africa.
Gordon AudleyP RaubenheimerG SymonsM MendelsonG MeintjesN A B NtusiS WassermanS DlaminiK DhedaR van Zyl-SmitG CalligaroPublished in: African journal of thoracic and critical care medicine (2024)
In resource-constrained settings, HFNO is a feasible non-invasive alternative to IMV and can be employed with favourable and consistent outcomes outside traditional critical care wards. It also confirms that the degree of gas exchange abnormality, and not pre-existing patient-related factors, circulating wave variant or provider experience, is the main predictor of HFNO failure.
Keyphrases
- respiratory failure
- extracorporeal membrane oxygenation
- south africa
- mechanical ventilation
- coronavirus disease
- sars cov
- healthcare
- primary care
- palliative care
- hiv positive
- intensive care unit
- case report
- type diabetes
- metabolic syndrome
- hepatitis c virus
- adipose tissue
- skeletal muscle
- room temperature
- insulin resistance
- weight loss
- human immunodeficiency virus
- chronic pain
- hiv infected