Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields.

Manjari PandeyJoanne XiuSandeep MittalJia ZengMichelle SaulSantosh KesariAmir AzadiHerbert NewtonKarina DenizKatherine LadnerAshley SumrallW Michael KornEmil Lou

Published in: Neuro-oncology advances (2022)

These results shed light on potential driver and passenger mutations in GB that can be validated as predictive biomarkers of response to TTFields treatment, and provide an objective and testable genomic-based approach to assessing response.

Keyphrases

copy number
gene expression
dna methylation
combination therapy