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Biphasic effects of cannabis and cannabinoid therapy on pain severity, anxiety, and sleep disturbance: a scoping review.

Alexander ShustorovichJamie CorroonMark S WallaceMichelle Sexton
Published in: Pain medicine (Malden, Mass.) (2024)
This scoping review reports on biphasic effects of cannabinoids related to pain, sleep, and anxiety. Dose-response relationships are present, but we found gaps in the current literature with regard to biphasic effects of cannabinoids in humans. There is a lack of prospective research in humans exploring this specific relationship.
Keyphrases
  • sleep quality
  • chronic pain
  • pain management
  • neuropathic pain
  • physical activity
  • systematic review
  • depressive symptoms
  • stem cells
  • spinal cord
  • mesenchymal stem cells
  • adverse drug
  • cell therapy
  • smoking cessation