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Chemotherapy-induced Sinusoidal Injury (CSI) score: a novel histologic assessment of chemotherapy-related hepatic sinusoidal injury in patients with colorectal liver metastasis.

Heather L StevensonMariana M PratsEizaburo Sasatomi
Published in: BMC cancer (2017)
The CSI score, calculated using an immunohistochemical panel consisting of CD34, SMA, and GS, may serve as an objective marker of chemotherapy-induced sinusoidal injury and could help diagnose this peculiar form of liver injury.
Keyphrases
  • chemotherapy induced
  • liver injury
  • drug induced
  • squamous cell carcinoma
  • locally advanced
  • rectal cancer