PTPRH Alleviates Airway Obstruction and Th2 Inflammation in Asthma as a Protective Factor.

Feng-Jia ChenLi-Juan DuZhimin ZengXin-Yan HuangChang-Yi XuWei-Ping TanCan-Mao XieYu-Xia LiangYu-Biao Guo

Published in: Journal of asthma and allergy (2022)

PTPRH reduces MUC5AC secretion to alleviate airway obstruction in asthma via potential phosphorylating of EGFR/ERK1/2/AKT signaling pathway, which may provide possible therapeutic implications for asthma.

Keyphrases

signaling pathway
chronic obstructive pulmonary disease
lung function
allergic rhinitis
pi k akt
cell proliferation
small cell lung cancer
oxidative stress
epithelial mesenchymal transition
epidermal growth factor receptor
air pollution