Brain, cognitive, and physical disability correlates of decreased quality of life in patients with Huntington's disease.
Estefanía JuncaMariana PinoHernando Santamaría-GarcíaSandra BaezPublished in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2022)
HD patients exhibit greater GM volume loss as well as lower QoL scores compared to caregivers and controls. However, caregivers displayed lower scores in QoL scores than controls, with years of education being a significant predictor. Our results reflect a first attempt to investigate the relationships among QoL, GM volumes, and other important factors in an HD and HD caregiver sample.