Correlation of Low Levels of α-1 Antitrypsin and Elevation of Neutrophil to Lymphocyte Ratio with Higher Mortality in Severe COVID-19 Patients.
Ghazaleh ShimiGolbon SohrabKatayoun PourvaliArman GhorbaniFarinaz Hosseini BalamKhalil RostamiHamid ZandPublished in: Mediators of inflammation (2021)
The current study revealed that severe COVID-19 patients had low serum AAT levels related to CRP values. Therefore, AAT response may be considered as a new mechanism by which some COVID-19 patients show immune dysregulation and more severe symptoms.