Switchable Enantioselectivity in Conjugate Alkyne Addition of β,γ-Unsaturated α-Keto Esters by Asymmetric Binary Acid Catalysis.

Depeng DuanMengdie TangMan WangHuixin QiuRan SongDaoshan YangJian Lv

Published in: Organic letters (2024)

Switchable enantioselectivity was uncovered in the enantioselective catalytic conjugate addition of β,γ-unsaturated α-keto esters with terminal alkynes to the chiral Lewis acid complex of In(BF 4 ) 3 and chiral phosphoric acid.

Keyphrases

ionic liquid
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